This may be already known, but I found this.
It puts a "Run in Debugger" pick in explorer to allow the opening of any .exe by your debugger.

Of course, you'll need to adjust the path for your debugger.

REGEDIT4


@="Run in Debugger"

@="\"C:\\OllyDbg_2\\ollydbg.exe\" \"%1\""
Posted on 2009-10-02 14:30:52 by skywalker